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Article

Dopamine-related genes and their relationships to monoamine metabolites in CSF.

Biological psychiatry - 15 Nov 1996

Jönsson E, Sedvall G, Brené S, Gustavsson J P, Geijer T, Terenius L, Crocq M A, Lannfelt L, Tylec A, Sokoloff P, Schwartz J C, Wiesel F A

Abstract excerpt

Monoamine metabolite (MM) levels in lumbar cerebrospinal fluid (CSF) are extensively used as indirect estimates of monoamine turnover in the brain. In this study we investigated genotypes for DNA polymorphisms in the D2 (DRD2), D3 (DRD3), and D4 (DRD4) dopamine receptor and tyrosine hydroxylase (TH) genes and their relationships to CSF MM in healthy volunteers (n = 66). Concentrations of homovanillic acid (HVA),...

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Source

Identifiers

PMID: 8915563
DOI: 10.1016/0006-3223(95)00581-1

Genes

DRD2
DRD3
DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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