Article
Phenotypic features of children with neurodevelopmental diseases in relation to biogenic amines.
Respiratory physiology & neurobiology - 1 Apr 2015
Szymańska Krystyna, Kuśmierska Katarzyna, Nowacka Maria, Sykut-Cegielska Jolanta, Demkow Urszula
Abstract excerpt
Disruption of monoamines metabolism leads to diverse manifestations, including developmental, movement and respiratory dysfunctions. We aimed to correlate clinical phenotypes of 55 children with neurodevelopmental disorders with dopamine (HVA) and serotonin (5-HIIA) metabolites in CSF. Decreased level of at least one metabolite was documented in 49.1% patients. Both metabolites were significantly lower in...
Topics
- Adolescent
- Adult
- Biogenic Amines
- Child
- Child, Preschool
- Disease Progression
- Female
- Follow-Up Studies
- Humans
- Infant
- Logistic Models
- Male
- Multivariate Analysis
- Neurodevelopmental Disorders
- Phenotype
- Young Adult
