Article
Variations in the vesicular monoamine transporter 1 gene (VMAT1/SLC18A1) are associated with bipolar i disorder.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Dec 2006
Lohoff Falk W, Dahl John P, Ferraro Thomas N, Arnold Steven E, Gallinat Jürgen, Sander Thomas, Berrettini Wade H
Abstract excerpt
The vesicular monoamine transporter 1 gene (VMAT1/SLC18A1) maps to the shared bipolar disorder (BPD)/schizophrenia (SZ) susceptibility locus on chromosome 8p21. Vesicular monoamine transporters are involved in transport of monoamine neurotransmitters which have been postulated to play a relevant role in the etiology of BPD and/or SZ. Variations in the VMAT1 gene might affect transporter function and/or expression...
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