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Article

Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing.

Antimicrobial agents and chemotherapy - 1 Aug 2014

Chou Sunwen, Ercolani Ronald J, Sahoo Malaya K, Lefterova Martina I, Strasfeld Lynne M, Pinsky Benjamin A

Abstract excerpt

In immunosuppressed hosts, the development of multidrug resistance complicates the treatment of cytomegalovirus (CMV) infection. Improved genotypic detection of impending drug resistance may follow from recent technical advances. A severely T-cell-depleted patient with chronic lymphocytic leukemia developed CMV pneumonia and high plasma viral loads that were poorly responsive to antiviral therapy. Serial plasma...

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Identifiers

PMID: 24890586
DOI: 10.1128/AAC.03214-14
PMCID: PMC4135977

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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