Article
Polymorphisms in the annexin A5 gene promoter in Japanese women with recurrent pregnancy loss.
Molecular human reproduction - 1 Jul 2011
Miyamura Hironori, Nishizawa Haruki, Ota Sayuri, Suzuki Machiko, Inagaki Ayaka, Egusa Hiromi, Nishiyama Sachie, Kato Takema, Pryor-Koishi Kanako, Nakanishi Isao, Fujita Tomio, Imayoshi Yuzo, Markoff Arseni, Yanagihara Itaru, Udagawa Yasuhiro, Kurahashi Hiroki
Abstract excerpt
Recent findings have raised the possibility that polymorphisms within the annexin A5 gene (ANXA5) promoter contribute to the etiology of recurrent pregnancy loss (RPL). In our present study, 243 Japanese women who had suffered more than three fetal losses and a group of 119 fertile controls were genotyped for four ANXA5 gene promoter single-nucleotide polymorphisms (SNPs; SNP1-4: g.-467G >A, g.-448A>C, g.-422T>C,...
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