Article
Correlation of single nucleotide polymorphisms in the promoter region of the ANXA5 (annexin A5) gene with recurrent miscarriages in women of Greek origin.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians - 1 May 2020
Dryllis G, Giannopoulos A, Zoi C, Pouliakis A, Logothetis E, Voulgarelis M, Zoi K, Kouskouni E, Dinou A, Stavropoulos-Giokas C, Kreatsas G, Konstantopoulos K, Politou M
Abstract excerpt
Background: Recent findings show that a number of single nucleotide polymorphisms (SNPs) within the promoter region of the annexin A5-gene (ANXA5) reduce the expression of the reporter gene and so they display a significant association with recurrent pregnancy loss (RPL).Objective: The objective of the present study aimed to address the contribution of ANXA5 M2 haplotype consisting of four minor alleles: (SNP1:...
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