Article
Genetic analysis of ANXA5 haplotype and its effect on recurrent pregnancy loss.
Molecular medicine reports - 1 Feb 2022
Cai Zhuhua, Zheng Xiuying, Chen Yan, Chen Fengdan, Chen Liangmiao, Deng Xiaohui
Abstract excerpt
Recurrent pregnancy loss (RPL) is often associated with dysregulated Annexin A5 (ANXA5) expression. Moreover, the variants of Anxa5, a protein that is enriched in the placenta to prevent coagulation, have been reported to affect RPL risks. The haplotypes M1 [including single nucleotide polymorphisms (SNPs) 1A/C and 27T/C] and M2 (including SNPs 19G/A, 1A/C, 27T/C and 76G/A) of ANXA5 were also reported to affect...
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