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Article

Haplotype M2 in the annexin A5 (ANXA5) gene and the occurrence of obstetric complications

1 Jan 2009

Abstract excerpt

Inherited or acquired thrombophilias have been largely explored as a cause of pregnancy complications. However, pathogenesis of obstetric complications, as fetal loss and pregnancy-related hypertensive disorders is still partly unexplained. Recently, a common haplotype (M2) within the annexin A5 (ANXA5) gene has been described as a risk factor in recurrent fetal losses (RFL). It has been demonstrated to reduce...

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Identifiers

PMID: 19652881
DOI: 10.1160/th09-02-0123

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Haplotype M2 in the annexin A5 (ANXA5) gene and the occurrence of obstetric complicationsPMID 19652881Read ↗

Further insights into the role of the annexin A5 M2 haplotype as recurrent pregnancy loss factor, assessing timing of miscarriage and partner risk.Semantic proximity Read ↗

Genetic analysis of ANXA5 haplotype and its effect on recurrent pregnancy loss.Semantic proximity Read ↗

Maternal carriers of the ANXA5 M2 haplotype are exposed to a greater risk for placenta-mediated pregnancy complications.Semantic proximity Read ↗

A common haplotype of the annexin A5 (ANXA5) gene promoter is associated with recurrent pregnancy lossSemantic proximity Read ↗

Annexin A5 Promoter Haplotype M2 Is Not a Risk Factor for Recurrent Pregnancy Loss in Northern Europe.Semantic proximity Read ↗

Association between ANXA5 haplotypes and the risk of recurrent pregnancy loss.Semantic proximity Read ↗

Assessment of M2/ANXA5 haplotype as a risk factor in couples with placenta-mediated pregnancy complications.Semantic proximity Read ↗

Investigation of the Annexin A5 M2 haplotype in 500 white European couples who have experienced recurrent spontaneous abortion.Semantic proximity Read ↗

Reduced allele specific annexin A5 mRNA levels in placentas carrying the M2/ANXA5 allele.Semantic proximity Read ↗

Contribution of fetal ANXA5 gene promoter polymorphisms to the onset of pre-eclampsia.Semantic proximity Read ↗

The M2 haplotype in the ANXA5 gene is an independent risk factor for idiopathic small-for-gestational age newborns.Semantic proximity Read ↗

Genetic variations in the annexin A5 gene and the risk of pregnancy-related venous thrombosis.Semantic proximity Read ↗

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