The Identification of Cis-Regulatory Sequence Motifs in Gene Promoters Based on SNP Information.

Abstract excerpt

Conservation of particular molecular sequence motifs throughout evolution is a strong indicator of their functional relevance as selective pressure likely prevented the accumulation of mutations. Known as "phylogenetic footprinting", this rationale has been exploited for the identification of novel functional motifs using sequence information from sequence alignments of diverse species, in particular...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Binding Sites
• Share to Conserved Sequence
• Share to Nucleotide Motifs