Article

Identification of upstream transcription factor binding sites in orthologous genes using mixed Student’s <i>t</i> -test statistics

2021-12-21

Abstract excerpt

<h4>Background</h4> Transcription factor (TF) regulates the transcription of DNA to messenger RNA by binding to upstream sequence motifs. Identifying the locations of known motifs in whole genomes is computationally intensive. <h4>Methodology/Principal Findings</h4> This study presents a computational tool, named “Grit”, for screening TF-binding sites (TFBS) by coordinating transcription factors to their promote...

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Literature Corpus work: 47a2d812-20c1-516c-b779-4d91eaf81dda
DOI: 10.1101/2021.12.20.473422

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