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Article

Landscape and Dynamics of Transcription Initiation in the Malaria Parasite Plasmodium falciparum

1 Mar 2016

Abstract excerpt

A comprehensive map of transcription start sites (TSSs) across the highly AT-rich genome of P. falciparum would aid progress toward deciphering the molecular mechanisms that underlie the timely regulation of gene expression in this malaria parasite. Using high-throughput sequencing technologies, we generated a comprehensive atlas of transcription initiation events at single-nucleotide resolution during the...

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PMID: 26947071
DOI: 10.1016/j.celrep.2016.02.025

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