Article
Variation and constraints in species-specific promoter sequences.
Journal of theoretical biology - 21 Dec 2014
Calistri Elisa, Buiatti Marcello, Livi Roberto
Abstract excerpt
A vast literature is nowadays devoted to the search of correlations between transcription related functions and the composition of sequences upstream the Transcription Start Site. Little is known about the possible functional effects of nucleotide distributions on the conformational landscape of DNA in such regions. We have used suitable statistical indicators for identifying sequences that may play an important...
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