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<i>Lactobacillus reuteri</i> -produced cyclic dipeptides quench <i>agr</i> -mediated expression of toxic shock syndrome toxin-1 in staphylococci

31 Jan 2011

Abstract excerpt

The production of the staphylococcal exotoxin toxic shock syndrome toxin-1 (TSST-1) by Staphylococcus aureus has been associated with essentially all cases of menstruation-associated toxic shock syndrome (TSS). In this work, we show that the human vaginal isolate Lactobacillus reuteri RC-14 produces small signaling molecules that are able to interfere with the staphylococcal quorum-sensing system agr, a key...

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Identifiers

PMID: 21282650
DOI: 10.1073/pnas.1017431108

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<i>Lactobacillus reuteri</i> -produced cyclic dipeptides quench <i>agr</i> -mediated expression of toxic shock syndrome toxin-1 in staphylococciPMID 21282650Read ↗

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