Article

Elucidating the <i>Staphylococcus aureus</i> TSST-1 regulatory network as a response to vaginal pH

2025-09-06

Abstract excerpt

<h4>ABSTRACT</h4> Menstrual toxic shock syndrome (mTSS) is a life-threatening disease caused by the Staphylococcus aureus superantigen TSST-1. At menstruation, the typical acidic vaginal environment rises to near neutral pH, which allows for optimal TSST-1 production. However, the regulation network which alters toxin production in response to pH is largely unknown, despite the importance of this cue in the vagi...

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Literature Corpus work: 44094832-8fa8-5ca0-9ec2-6d21930bb03f
DOI: 10.1101/2025.09.06.674626

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