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Article

Polymorphisms of interferon-inducible genes OAS associated with interferon-α treatment response in chronic HBV infection.

Antiviral research - 1 Mar 2011

Ren Shan, Yu Haibin, Zhang Hongwei, Liu Ying, Huang Yanxiang, Ma Lina, Wei Lai, Wu Hao, Chen Xinyue

Abstract excerpt

To evaluate the role of host single nucleotide polymorphisms (SNPs) of 2',5'-oligoadenylate synthetase (OAS) in predicting IFN response in patients with HBV infection, OAS gene and four SNPs were examined in 363 patients with chronic HBV infection (including 41 patients with HBsAg seroconversion) and 57 healthy controls. One SNP and three haplotypes were identified after adjustment for age, sex, HBV DNA. The...

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Share to 2',5'-Oligoadenylate Synthetase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21277331
DOI: 10.1016/j.antiviral.2011.01.006

Genes

OAS3
OAS2
OASL

Provenance

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