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Article

Impact of IL28B and OAS gene family polymorphisms on interferon treatment response in Caucasian children chronically infected with hepatitis B virus.

World journal of gastroenterology - 7 Nov 2016

Domagalski Krzysztof, Pawłowska Małgorzata, Zaleśna Agnieszka, Pilarczyk Małgorzata, Rajewski Paweł, Halota Waldemar, Tretyn Andrzej

Abstract excerpt

AIM: To investigate the impact of IL28B and OAS gene polymorphisms on interferon treatment responses in children with chronic hepatitis B. METHODS: We enrolled 52 children (between the ages of 4 and 18) with hepatitis B e antigen-negative chronic hepatitis B (CHB), who were treated with pegylated interferon alfa for 48 wk. Single nucleotide polymorphisms in the OAS1 (rs1131476), OAS2 (rs1293747), OAS3...

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Identifiers

PMID: 27895405
DOI: 10.3748/wjg.v22.i41.9186
PMCID: PMC5107599

Genes

OASL
OAS1
OAS2
OAS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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