Article
Role of HLA-DP polymorphisms on chronicity and disease activity of hepatitis B infection in Southern Chinese.
PloS one - 1 Jan 2013
Wong Danny Ka-Ho, Watanabe Tsunamasa, Tanaka Yasuhito, Seto Wai-Kay, Lee Cheuk-Kwong, Fung James, Lin Che-Kit, Huang Fung-Yu, Lai Ching-Lung, Yuen Man-Fung
Abstract excerpt
BACKGROUND AND AIMS: The association between HLA-DP single nucleotide polymorphisms (SNPs) and chronic hepatitis B virus (HBV) infection varies between different populations. We aimed to study the association between HLA-DP SNPs and HBV infection and disease activity in the Chinese population of Hong Kong. METHODS: We genotyped SNPs rs3077 (near HLA-DPA1) and rs9277378 and rs3128917 (both near HLA-DPB1) in 500...
Read the complete abstract on PubMed