Article
Search for genetic association between IgA nephropathy and candidate genes selected by function or by gene mapping at loci IGAN2 and IGAN3.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jun 2012
Bertinetto Francesca Eleonora, Calafell Francesc, Roggero Stefano, Chidichimo Rossella, Garino Elena, Marcuccio Cristina, Coppo Rosanna, Scolari Francesco, Frascá Giovanni Maria, Savoldi Silvana, Schena Francesco Paolo, Amoroso Antonio
Abstract excerpt
BACKGROUND: IgA nephropathy (IgAN) is not generally considered a hereditary disease, even though extensive evidence suggests an undefined genetic influence. Linkage analysis identified a number of genome regions that could contain variations linked to IgAN. METHODS: In this case-control association study, genes possibly involved in the development of IgAN were investigated. DNA samples from 460 North Italian...
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