Article
Immunotherapy with a tumor-infiltrating lymphocyte clone, soluble antigen, and cyclophosphamide.
Archives of surgery (Chicago, Ill. : 1960) - 1 Dec 1992
Komichi H, Smith S, Kahan B D
Abstract excerpt
A tumor-specific cytotoxic T-lymphocyte clone derived from bulk cultures of tumor-infiltrating lymphocytes attenuated the outgrowth of methylcholanthrene (MCA)-induced fibrosarcomas in C3H/HeJ mice. In 4-hour chromium 51-release assays, bulk cultures of tumor-infiltrating lymphocytes showed nonsp...
Topics
- Animals
- Antibodies, Monoclonal
- Antigens, Neoplasm
- Clone Cells
- Combined Modality Therapy
- Cyclophosphamide
- Female
- Fibrosarcoma
- Histocompatibility Antigens
- Immunotherapy, Adoptive
- Lymphocytes, Tumor-Infiltrating
- Mice
- Mice, Inbred C3H
- Mice, Inbred Strains
- Phenotype
- Spleen
- T-Lymphocytes, Cytotoxic