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Article

Suppression of proliferation, tumorigenicity and metastasis of lung cancer cells after their transduction by interferon-beta gene in baculovirus vector.

Cytokine - 1 Feb 2015

Lykhova Alexandra A, Kudryavets Yuri I, Strokovska Ludmila I, Bezdenezhnykh Natalia A, Semesiuk Nadiia I, Adamenko Inna N, Anopriyenko Olga V, Vorontsova Ada L

Abstract excerpt

BACKGROUND: Gene therapy represents an interesting alternative treatment for cancers. Interferon-beta is well known as a multifunctional cytokine that provides antiviral, antiproliferative, antiangiogenic and immunomodulating effects. For this reason introduction of this cytokine gene in baculovirus vector is seen as a rather promising tool for anticancer therapy. AIM: Investigation of biological behavior in...

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PMID: 25497739
DOI: 10.1016/j.cyto.2014.10.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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