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Article

A20, ABIN-1/2, and CARD11 mutations and their prognostic value in gastrointestinal diffuse large B-cell lymphoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Mar 2011

Dong Gehong, Chanudet Estelle, Zeng Naiyan, Appert Alex, Chen Yun-Wen, Au Wing-Yan, Hamoudi Rifat A, Watkins A James, Ye Hongtao, Liu Hongxiang, Gao Zifen, Chuang Shih-Sung, Srivastava Gopesh, Du Ming-Qing

Abstract excerpt

PURPOSE: Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous group of aggressive lymphomas with the activated B-cell-like subtype characterized by constitutive NF-κB activation. Activating mutations of CARD11 and inactivating mutations of A20 are frequent events in DLBCL. However, the full extent of genetic alterations in the NF-κB pathway regulators and their potential prognostic value in DLBCL remain to be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21266526
DOI: 10.1158/1078-0432.CCR-10-1859

Genes

CARD11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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