Article
Disruption of reelin signaling alters mammary gland morphogenesis.
Development (Cambridge, England) - 1 Feb 2011
Khialeeva Elvira, Lane Timothy F, Carpenter Ellen M
Abstract excerpt
Reelin signaling is required for appropriate cell migration and ductal patterning during mammary gland morphogenesis. Dab1, an intracellular adaptor protein activated in response to reelin signaling, is expressed in the developing mammary bud and in luminal epithelial cells in the adult gland. Reelin protein is expressed in a complementary pattern, first in the epithelium overlying the mammary bud during...
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