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Article

Rescue of ataxia and preplate splitting by ectopic expression of Reelin in reeler mice.

Neuron - 14 Feb 2002

Magdaleno Susan, Keshvara Lakhu, Curran Tom

Abstract excerpt

The gene mutated in reeler (reelin) encodes a protein secreted by neurons in the developing brain that controls laminar positioning of migrating cells in the CNS by an unknown mechanism. To investigate Reelin function, we used the nestin promoter to express Reelin ectopically in the ventricular zone and other brain regions in transgenic mice. In the presence of the endogenous protein, ectopic Reelin did not alter...

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Source

Identifiers

PMID: 11856531
DOI: 10.1016/s0896-6273(02)00582-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Rescue of ataxia and preplate splitting by ectopic expression of Reelin in reeler mice.PMID 11856531Read ↗

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