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Article

The MHC, disease and selection.

Immunology letters - 30 Jun 2011

Trowsdale John

Abstract excerpt

Given large sample sizes, whole genome screens are now able to identify even quite modest contributions of common human genetic variation to disease. These approaches, made possible by the development of high-throughput, dense SNP genotyping, find few associations stronger than those for the human MHC, in multigenic autoimmune conditions. They confirm earlier findings that the major variants affecting...

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Identifiers

PMID: 21262263
DOI: 10.1016/j.imlet.2011.01.002

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