Article
Several genes in the extended human MHC contribute to predisposition to autoimmune diseases.
Current opinion in immunology - 1 Oct 2005
Lie Benedicte A, Thorsby Erik
Abstract excerpt
Autoimmune diseases, such as type 1 diabetes, rheumatoid arthritis, psoriasis and systemic lupus erythematosus, affect approximately 4% of the population in industrialized countries, and are characterized by an immune-mediated destruction of autologous cells and/or tissues. More knowledge is needed to prevent and treat this large group of diseases. Unravelling the genetic predisposing factors is important in this...
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