Identifying genetic determinants of autoimmunity and immune dysregulation.

doi:10.1016/j.coi.2015.09.001

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Article

Identifying genetic determinants of autoimmunity and immune dysregulation.

Current opinion in immunology - 1 Dec 2015

Lucas Carrie L, Lenardo Michael J

Abstract excerpt

Common autoimmune diseases are relatively heterogeneous with both genetic and environmental factors influencing disease susceptibility and progression. As the populations in developed countries age, these chronic diseases will become an increasing burden in human suffering and health care costs. By contrast, rare immune diseases that are severe and develop early in childhood are frequently monogenic and fully...

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Identifiers

PMID: 26433354
DOI: 10.1016/j.coi.2015.09.001
PMCID: PMC5583726

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.