Article
Association of TIMP2 418 G/C and MMP Gene Polymorphism with Risk of Urinary Cancers: Systematic Review and Meta-analysis.
Genetic testing and molecular biomarkers - 1 Mar 2024
Gowtham Pemula, Girigoswami Koyeli, Thirumalai Anbazhagan, Harini Karthick, Pallavi Pragya, Girigoswami Agnishwar
Abstract excerpt
Aim: The matrix metalloproteinases (MMPs) inhibit tissue inhibitors of metalloproteinases (TIMPs), playing a notable role in various biological processes, and mutations in TIMP2 genes impact a variety of urinary cancers. In this study, we analyze and evaluate the potential involvement of the TIMP2 418 G/C and MMP gene polymorphism in the etiology of urinary cancer. Methodology: For suitable case-control studies,...
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