Article
rs3918242 variant genotype frequency and increased TIMP-2 and MMP-9 expression are positively correlated with cancer invasion in urinary bladder cancer.
Cellular and molecular biology (Noisy-le-Grand, France) - 30 Sept 2017
Pençe S, Özbek E, Ozan Tiryakioğlu N, Ersoy Tunali N, Pençe H H, Tunali H
Abstract excerpt
To study the role of MMP9 and TIMP2 genotypes and expression in predisposition to bladder cancer and relation with metastasis. 100 urinary bladder cancer patients and 100 healthy controls were included in the study. rs3918242 and rs8179090 genotypes were determined with PCR-RFLP. Quantitative real-time polymerase chain reaction was employed to assess the MMP-9 and TIMP-2 expression in tumors and adjacent healthy...
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