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Article

No correlation between TIMP2 -418 G>C polymorphism and increased risk of cancer: evidence from a meta-analysis.

PloS one - 1 Jan 2014

Mandal Raju K, Akhter Naseem, Haque Shafiul, Panda Aditya K, Mittal Rama D, Alqumber Mohammed A A

Abstract excerpt

AIM: Tissue inhibitor of metalloproteinase (TIMP2) is involved in the regulation of matrix metalloproteinase 2 (MMP2) and shown to implicate in cancer development and progression. The results from the published studies based on the association between TIMP2 -418 G>C polymorphism and cancer risk are inconsistent. In this meta-analysis, we aimed to evaluate the potential association between TIMP2 -418 G>C...

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Identifiers

PMID: 25136829
DOI: 10.1371/journal.pone.0088184
PMCID: PMC4138026

Genes

TIMP2
MMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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