Article
TAZ is a novel oncogene in non-small cell lung cancer.
Oncogene - 5 May 2011
Zhou Z, Hao Y, Liu N, Raptis L, Tsao M-S, Yang X
Abstract excerpt
Transcriptional coactivator with PDZ-binding motif (TAZ) is a transcriptional coactivator involved in the differentiation of stem cell as well as the development of multiple organs. Recently, TAZ has also been identified as a major component of the novel Hippo-LATS tumor suppressor pathway and to function as an oncogene in breast cancer. We show for the first time that TAZ is an oncogene in non-small cell lung...
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