Article

Division of labor between YAP and TAZ in non-small cell lung cancer

2020-01-13

Abstract excerpt

Lung cancer is the leading cause of cancer-related deaths worldwide. The paralogous transcriptional cofactors Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ, also called WWTR1), the main downstream effectors of the Hippo signal transduction pathway, are emerging as pivotal determinants of malignancy in lung cancer. Traditionally, studies have tended to consider YAP and TA...

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Literature Corpus work: 422b754a-60ae-5c70-a550-f14a563e3c99
DOI: 10.1101/2020.01.12.894733

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