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Article

Overexpression of CARMA3 in Non-Small-Cell Lung Cancer Is Linked for Tumor Progression

15 May 2012

Abstract excerpt

We aimed to investigate the clinical significance of the expression of novel scaffold protein CARMA3 in non-small-cell lung cancer (NSCLC) and the biological function of CARMA3 in NSCLC cell lines. We observed moderate to high CARMA3 staining in 68.8% of 141 NSCLC specimens compared to corresponding normal tissues. The overexpression of CARMA3 was significantly correlated with TNM stage (P = 0.022) and tumor...

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PMID: 22615840
DOI: 10.1371/journal.pone.0036903

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