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Article

YAP and TAZ modulate cell phenotype in a subset of small cell lung cancer.

Cancer science - 1 Dec 2016

Horie Masafumi, Saito Akira, Ohshima Mitsuhiro, Suzuki Hiroshi I, Nagase Takahide

Abstract excerpt

Small cell lung cancer (SCLC) is a highly aggressive and metastatic malignancy that shows rapid development of chemoresistance and a high rate of recurrence. Recent genome and transcriptome studies have provided the whole landscape of genomic alterations and gene expression changes in SCLC. In light of the inter-individual heterogeneity of SCLC, subtyping of SCLC might be helpful for prediction of therapeutic...

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Identifiers

PMID: 27627196
DOI: 10.1111/cas.13078
PMCID: PMC5198951

Genes

AJUBA
ASCL1

Provenance

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