Article
A candidate gene study revealed sex-specific association between the OLR1 gene and carotid plaque.
Stroke - 1 Mar 2011
Wang Liyong, Yanuck Danielle, Beecham Ashley, Gardener Hannah, Slifer Susan, Blanton Susan H, Sacco Ralph L, Rundek Tatjana
Abstract excerpt
BACKGROUND AND PURPOSE: Sex differences have been recognized in stroke risk; however, the sex-dependent genetic contribution to stroke is unclear. We sought to examine the sex-dependent associations between genes involved in lipid metabolism and carotid atherosclerotic plaque, a subclinical precursor of stroke. METHODS: For the Genetic Determinant of Subclinical Carotid Disease study, 287 Dominicans ascertained...
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