Article
BHMT gene polymorphisms as risk factors for cleft lip and cleft palate in a Chinese population.
Biomedical and environmental sciences : BES - 1 Apr 2011
Hu Ying, Chen Erjun, Mu Yue, Li Jinlu, Chen Renji
Abstract excerpt
OBJECTIVE: Convincing evidence suggests a link between increased risk of nonsyndromic cleft lip with or without cleft palate (NSCL/P) and low intake of folic acid by the mother during pregnancy. The present study was designed to explore if genetic variation in the betaine-homocysteine methyltransferase (BHMT) gene contributes to NSCL/P. METHODS: DNA was obtained from 166 individuals with NSCL/P and 285 healthy...
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