Article
Role of NQO1 609C>T and NQO2 -3423G>A gene polymorphisms in esophageal cancer risk in Kashmir valley and meta analysis.
Molecular biology reports - 1 Sept 2012
Malik Manzoor Ahmad, Zargar Showkat Ali, Mittal Balraj
Abstract excerpt
Esophageal cancer (EC) is a complex multifactorial disorder, where environmental and genetic factors play major role. NADPH:quinone oxidoreductase 1 (NQO1) and NRH:quinone oxidoreductase 2 (NQO2) are phase II cytosolic enzymes that catalyze metabolism of quinones, important in the detoxification of environmental carcinogens. A case-control study was performed to investigated the associations of NQO1 609C>T and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
