Article
Role of NQO1 609C>T and NQO2 -3423G>A gene polymorphisms in esophageal cancer risk in Kashmir valley and meta analysis.
Molecular biology reports - 1 Sept 2012
Malik Manzoor Ahmad, Zargar Showkat Ali, Mittal Balraj
Abstract excerpt
Esophageal cancer (EC) is a complex multifactorial disorder, where environmental and genetic factors play major role. NADPH:quinone oxidoreductase 1 (NQO1) and NRH:quinone oxidoreductase 2 (NQO2) are phase II cytosolic enzymes that catalyze metabolism of quinones, important in the detoxification...
Topics
- Aged
- Alleles
- Asian People
- Case-Control Studies
- Epistasis, Genetic
- Esophageal Neoplasms
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- India
- Male
- Middle Aged
- NAD(P)H Dehydrogenase (Quinone)
- Odds Ratio
- Polymorphism, Single Nucleotide
- Quinone Reductases
- Risk