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Article

Hyaluronan production by means of Has2 gene expression in chondrocytes is essential for long bone development.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Feb 2011

Moffatt Pierre, Lee Eunice R, St-Jacques Benoit, Matsumoto Kazu, Yamaguchi Yu, Roughley Peter J

Abstract excerpt

Mice possessing no Has2 expression in chondrocytes died near birth and displayed abnormalities throughout their skeleton. By embryonic day 18.5, the long bones were short and wide, and possessed excessive mineralization within their diaphysis, with little evidence of diaphyseal bone modeling. How...

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Identifiers

PMID: 21246657
DOI: 10.1002/dvdy.22529

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21246657-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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