Article
Tuning the cavity of cyclodextrins: altered sugar adaptors in protein pores.
Journal of the American Chemical Society - 16 Feb 2011
Li Wen-Wu, Claridge Timothy D W, Li Qiuhong, Wormald Mark R, Davis Benjamin G, Bayley Hagan
Abstract excerpt
Cyclodextrins (CDs) have been widely used in host-guest molecular recognition because of their chiral and hydrophobic cavities. For example, β-cyclodextrin (βCD) lodged as a molecular adaptor in protein pores such as α-hemolysin (αHL) is used for stochastic sensing. Here, we have tuned the cavity...
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