Article
Ion selectivity of alpha-hemolysin with a beta-cyclodextrin adapter. I. Single ion potential of mean force and diffusion coefficient.
The journal of physical chemistry. B - 21 Jan 2010
Luo Yun, Egwolf Bernhard, Walters D Eric, Roux Benoît
Abstract excerpt
The alpha-hemolysin (alphaHL) is a self-assembling exotoxin that binds to the membrane of a susceptible host cell and causes its death. Experimental studies show that electrically neutral beta-cyclodextrin (betaCD) can insert into the alphaHL channel and significantly increase its anion selectivi...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
