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Article

Impact of distant charge reversals within a robust beta-barrel protein pore.

The journal of physical chemistry. B - 8 Jul 2010

Mohammad Mohammad M, Movileanu Liviu

Abstract excerpt

Among all beta-barrel pores, staphylococcal alpha-hemolysin (alphaHL), a heptameric transmembrane protein of known high-resolution crystal structure, features a high stability in planar lipid bilayers under a wide range of harsh experimental conditions. Here, we employed single-channel electrical recordings and standard protein engineering to explore the impact of two distant charge reversals within the interior...

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Identifiers

PMID: 20540583
DOI: 10.1021/jp101311s
PMCID: PMC2907733

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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