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Article

Stochastic detection of enantiomers.

Journal of the American Chemical Society - 23 Aug 2006

Kang Xiao-Feng, Cheley Stephen, Guan Xiyun, Bayley Hagan

Abstract excerpt

The rapid quantification of the enantiomers of small chiral molecules is very important, notably in pharmacology. Here, we show that the enantiomers of drug molecules can be distinguished by stochastic sensing, a single-molecule detection technique. The sensing element is an engineered alpha-hemolysin protein pore, fitted with a beta-cyclodextrin adapter. By using the approach, the enantiomeric composition of...

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PMID: 16910655
DOI: 10.1021/ja063485l

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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