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Article

The de novo engineering of pyrrolysyl-tRNA synthetase for genetic incorporation of L-phenylalanine and its derivatives.

Molecular bioSystems - 1 Mar 2011

Wang Yane-Shih, Russell William K, Wang Zhiyong, Wan Wei, Dodd Lindsey E, Pai Pei-Jing, Russell David H, Liu Wenshe R

Abstract excerpt

Using evolved pyrrolysyl-tRNA synthetase-tRNA(CUA)(Pyl) pairs, L-phenylalanine, p-iodo-L-phenylalanine and p-bromo-L-phenylalanine have been genetically incorporated into proteins at amber mutation sites in E. coli.

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Source

Identifiers

PMID: 21234492
DOI: 10.1039/c0mb00217h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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