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Article

Expanding the genetic code.

Annual review of biophysics and biomolecular structure - 1 Jan 2006

Wang Lei, Xie Jianming, Schultz Peter G

Abstract excerpt

Recently, a general method was developed that makes it possible to genetically encode unnatural amino acids with diverse physical, chemical, or biological properties in Escherichia coli, yeast, and mammalian cells. More than 30 unnatural amino acids have been incorporated into proteins with high fidelity and efficiency by means of a unique codon and corresponding tRNA/aminoacyl-tRNA synthetase pair. These include...

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Identifiers

PMID: 16689635
DOI: 10.1146/annurev.biophys.35.101105.121507

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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