Article
Simplification of the genetic code: restricted diversity of genetically encoded amino acids.
Nucleic acids research - 1 Nov 2012
Kawahara-Kobayashi Akio, Masuda Akiko, Araiso Yuhei, Sakai Yoko, Kohda Atsushi, Uchiyama Masahiko, Asami Shun, Matsuda Takayoshi, Ishitani Ryuichiro, Dohmae Naoshi, Yokoyama Shigeyuki, Kigawa Takanori, Nureki Osamu, Kiga Daisuke
Abstract excerpt
At earlier stages in the evolution of the universal genetic code, fewer than 20 amino acids were considered to be used. Although this notion is supported by a wide range of data, the actual existence and function of the genetic codes with a limited set of canonical amino acids have not been addressed experimentally, in contrast to the successful development of the expanded codes. Here, we constructed artificial...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.