Ectopic expression of chloramphenicol acetyltransferase (CAT) in the cerebellum in mice transgenic for a carbonic anhydrase II promoter-CAT construct that is without apparent phenotypic effect.

doi:10.1002/mrd.1080270204

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Article

Ectopic expression of chloramphenicol acetyltransferase (CAT) in the cerebellum in mice transgenic for a carbonic anhydrase II promoter-CAT construct that is without apparent phenotypic effect.

Molecular reproduction and development - 1 Oct 1990

Erickson R P, Bevilacqua A, Venta P J, Karolyi J, Tashian R E

Abstract excerpt

We have developed six transgenic lines of mice with constructs containing presumptive 5' regulatory regions of carbonic anhydrase II (CA II). Four of the lines contained 1,100 bases of the 5' flanking region of the human CA II gene, and two transgenic lines resulted from a construct containing 500 bases of the 5' flanking region of the mouse CA II gene. Tissue-specific expression of the chloramphenicol...

Topics

Animals
Carbonic Anhydrases
Cerebellum
Chloramphenicol O-Acetyltransferase
Female
Gene Expression Regulation, Enzymologic
Homozygote
Male
Mice
Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Transgenic

Organ Specificity

Pedigree

Phenotype

Promoter Regions, Genetic

Recombinant Fusion Proteins

Regulatory Sequences, Nucleic Acid

Source

Open in PubMed

Identifiers

PMID: 2123391
DOI: 10.1002/mrd.1080270204

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2123391-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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