Aerosol gene delivery in vivo.

Abstract excerpt

The ability to express transgenes selectively within the lung will greatly facilitate the development of gene therapy for a variety of human diseases. We have demonstrated that aerosol administration of a chloramphenicol acetyltransferase (CAT) expression plasmid complexed to cationic liposomes produces high-level, lung-specific CAT gene expression in mice in vivo. Significant levels of CAT activity are seen in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Neonatal Respiratory Health Research
• Share to RNA Interference and Gene Delivery
• Share to Viral gastroenteritis research and epidemiology