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Article

Transgenic mice aberrantly expressing human ornithine decarboxylase gene.

The Journal of biological chemistry - 15 Oct 1991

Halmekytö M, Hyttinen J M, Sinervirta R, Utriainen M, Myöhänen S, Voipio H M, Wahlfors J, Syrjänen S, Syrjänen K, Alhonen L

Abstract excerpt

We have generated transgenic mice carrying human ornithine decarboxylase gene. Two different transgene constructs were used: (i) a 5'-truncated human ornithine decarboxylase gene and (ii) an intact human ornithine decarboxylase gene. Transgenic mice carrying the 5'-truncated gene did not express human ornithine decarboxylase-specific mRNA. Transgenic mice carrying the intact human ornithine decarboxylase gene...

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PMID: 1717470

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