Article
Phenotypic and functional similarity of gut intraepithelial and systemic T cells in a teleost fish.
Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2006
Bernard David, Six Adrien, Rigottier-Gois Lionel, Messiaen Sébastien, Chilmonczyk Stefan, Quillet Edwige, Boudinot Pierre, Benmansour Abdenour
Abstract excerpt
Gut-associated lymphocytes were described in fish, but their involvement in immune responses is still unknown. In rainbow trout, intraepithelial lymphocytes (IELs) are scattered between gut epithelial cells, but neither Peyer's patches nor mesenteric lymph nodes were identified. Rainbow trout IELs contain mainly T cells, because they expressed transcripts of T cell marker homologs of CD8, CD4, CD28, CD3epsilon,...
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