Article
Genome-Wide Pathway Analysis Identifies Genetic Pathways Associated with Psoriasis.
The Journal of investigative dermatology - 1 Mar 2016
Aterido Adrià, Julià Antonio, Ferrándiz Carlos, Puig Lluís, Fonseca Eduardo, Fernández-López Emilia, Dauden Esteban, Sánchez-Carazo José Luís, López-Estebaranz José Luís, Moreno-Ramírez David, Vanaclocha Francisco, Herrera Enrique, de la Cueva Pablo, Dand Nick, Palau Núria, Alonso Arnald, López-Lasanta María, Tortosa Raül, García-Montero Andrés, Codó Laia, Gelpí Josep Lluís, Bertranpetit Jaume, Absher Devin, Capon Francesca, Myers Richard M, Barker Jonathan N, Marsal Sara
Abstract excerpt
Psoriasis is a chronic inflammatory disease with a complex genetic architecture. To date, the psoriasis heritability is only partially explained. However, there is increasing evidence that the missing heritability in psoriasis could be explained by multiple genetic variants of low effect size from common genetic pathways. The objective of this study was to identify new genetic variation associated with psoriasis...
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