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Article

Homeostatic levels of SRC-2 and SRC-3 promote early human adipogenesis.

The Journal of cell biology - 10 Jan 2011

Hartig Sean M, He Bin, Long Weiwen, Buehrer Benjamin M, Mancini Michael A

Abstract excerpt

The related coactivators SRC-2 and SRC-3 interact with peroxisome proliferator activated receptor γ (PPARγ) to coordinate transcriptional circuits to promote adipogenesis. To identify potential coactivator redundancy during human adipogenesis at single cell resolution, we used high content analysis to quantify links between PPARγ, SRC-2, SRC-3, and lipogenesis. Because we detected robust increases and significant...

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Share to Adipocytes
Share to Adipogenesis
Share to Gene Knockdown Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Imaging, Three-Dimensional

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Source

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Identifiers

PMID: 21220509
DOI: 10.1083/jcb.201004026
PMCID: PMC3019557

Genes

SRC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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